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sundials solvers

sundials (suite of nonlinear and differential/algebraic equation solvers) are part of a freely available third-party package developed at . all other ode solvers used for simulation of simbiology^® models, such as ode45 and ode15s, are part of the matlab^® ode suite. simbiology currently (r2022a or later) uses sundials 5.7.0.

simbiology always uses the sundials solver to perform sensitivity analysis on a model, regardless of what you have selected as the in the configuration set.

in addition, if you are estimating model parameters using or the fit data program with one of these gradient-based estimation functions: fmincon, fminunc, lsqnonlin, or lsqcurvefit, simbiology uses the sundials solver by default to calculate sensitivities and use them to improve fitting. if you are using , you can turn off this sensitivity calculation feature by setting the name-value pair argument to false. however, if you are using the fit data program, you cannot turn off this feature. it is recommended that you keep the sensitivity analysis feature on whenever possible for more accurate gradient approximations and better parameter fits.

when you specify sundials for the solver, the software chooses one of two sundials solvers, cvode or ida, as appropriate for your model:

for more information on the sundials solvers, see .

related topics

• ode solvers
• stochastic solvers